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Thursday, April 4, 2013

Inflamation, Inflamation, Inflamation & Type 2 Diabetes?

More and more research keeps pointing the way to inflamation being a root cause of type 2 diabetes.


List of inflammatory diseases

A comprehensive list of inflammatory diseases would run to over 100, each of which have high levels of inflammation in the connective tissues, or degeneration of these tissues. These include...

ADD Type 2 Diabetes to this list.

  • Alzheimer's
  • ankylosing spondylitis
  • arthritis (osteoarthritis, rheumatoid arthritis (RA), psoriatic arthritis)
  • asthma
  • atherosclerosis
  • Crohn's disease
  • colitis
  • dermatitis
  • diverticulitis
  • fibromyalgia
  • hepatitis
  • irritable bowel syndrome (IBS)
  • systemic lupus erythematous (SLE)
  • nephritis
  • Parkinson's disease
  • ulcerative colitis
Inflammation is the end result of long term oxidative stress. The stress can be caused by emotional or physical trauma, and nutritional or environmental pollutants. In most cases it is something of everything.

Read more:
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The question is what has caused the oxidative stress. Food is a major culprit, sugar being the number one culprit as it causes glycation. Sugar in any form, ie starchy carbohydrates like potatoes, legumes, sweet fruit or root vegetables, sugar in drinks, sauces, tinned food etc., and in particular grains and anything made from them such as bread, cakes, biscuits, pasta etc. These all convert to glucose.
Glycation occurs when a sugar molecule binds to a protein or lipid molecule without the control of an enzyme. This impairs the function of the molecule, leading to advanced glycation endproducts (AGEs), resulting in many of our inflammatory diseases. AGE's are particularly high in diabetes.

Read more:
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Type 2 Diabetes: Inflammation, Not Obesity, Cause Of Insulin Resistance

ScienceDaily (Nov. 6, 2007) — Researchers at the University of California, San Diego (UCSD) School of Medicine have discovered that inflammation provoked by immune cells called macrophages leads to insulin resistance and Type 2 diabetes. Their discovery may pave the way to novel drug development to fight the epidemic of Type 2 diabetes associated with obesity, the most prevalent metabolic disease worldwide.

In recent years, it has been theorized that chronic, low-grade tissue inflammation related to obesity contributes to insulin resistance, the major cause of Type 2 diabetes. In research done in mouse models, the UCSD scientists proved that, by disabling the macrophage inflammatory pathway, insulin resistance and the resultant Type 2 diabetes can be prevented.

"Our research shows that insulin resistance can be disassociated from the increase in body fat associated with obesity," said Olefsky.
Macrophages, found in white blood cells in the bone marrow, are key players in the immune response. When these immune cells get into tissues, such as adipose (fat) or liver tissue, they release cytokines, which are chemical messenger molecules used by immune and nerve cells to communicate. These cytokines cause the neighboring liver, muscle or fat cells to become insulin resistant, which in turn can lead to Type 2 diabetes

You can help Fight inflamation with supplements such as Vitamin D3, Vitamin C and Vitamin E:

See my other posts on Vitamin D3 and why most people do NOT get enough.


Hos 4:6.............My people are destroyed for lack of knowledge.
Gal 3:13............Christ has redeemed us from the curse of the law, having become a curse for us...
1Pet 2:24..........(Jesus) bore our sins in His own body on the tree, that we, having died to sins, might live for righteousness -- by whose stripes you were healed.

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