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Saturday, November 10, 2012

HDL/LDL Ratio And Triglycerides

From a comment on my most recent post by Sam, I have decided to do a 2nd post on a promising answer to high triglycerides and LDL that is not optimal. It is a product called Sytrinol and is included in a product now being offered called CholesLo. SEE INFO BELOW:

Dan

"The Lord is gracious and full of compassion, slow to anger and great in mercy. The Lord is good to all, and His tender mercies are over all His works." (Psalm 145:8)

“For as the heavens are high above the earth, so great is His mercy toward those who fear Him … But the mercy of the Lord is from everlasting to everlasting on those who fear Him.” (Psalm 103:11,17)



Following is a LINK to a lengthy and very informative article about Sytrinol:

http://www.nutritionreview.org/library/sytrinol.html

EXCERPT:

Safety and Effects of Sytrinol™

Sytrinol™ was developed after 12 years of extensive research on polymethoxylated flavonoids, tocotrienols, and their effects on cardiovascular health. The health benefits of Sytrinol have been well demonstrated in in vitro, in vivo, and clinical studies. Animal toxicity studies have shown that Sytrinol is well tolerated, with no toxics effects following consumption of polymethoxylated flavones in amounts up to 1% of the diet – the equivalent of an 70 kg (150 lbs.) individual consuming almost 14 grams per day.
The cholesterol-lowering effects of Sytrinol were documented in a recent animal study published in the May 2004 issue of the Journal of Agricultural and Food Chemistry. Canadian researchers first induced hypercholesterolemia in hamsters to boost their cholesterol levels. The animals were then treated with either PMFs (tangeretin) or a combination of flavones (hesperidin and naringin). While the flavones were shown to lower cholesterol levels, the PMF formulation proved to be almost three times as effective. In hamsters receiving the tangeretin formula, total cholesterol levels declined by up to 27%, and LDL was reduced by 40%. And while HDL levels were unchanged, the net result was a significant improvement in the LDL/HDL ratio. (66)
The cardio-protective and cholesterol-lowering claims for Sytrinol™ are also supported by human trials. Two early trials, consisting of ten subjects each, measured the effects of Sytrinol in men and women diagnosed with hypercholesterolemia (elevated cholesterol) and screened to eliminate thyroid disorders, kidney disorders and diabetes. Subjects were instructed to maintain normal dietary habits and discontinue using vitamins, supplements and cholesterol-lowering medications for at least 6 weeks prior to, and during the study. Fasting blood samples were drawn at the onset and end of each 4-week trial, and plasma lipids profiles and other metabolic parameters were analyzed using standard methods.
The results from the first trial (Table 1) show that four weeks of treatment with Sytrinol (300 mg/day) caused significant reductions in: total cholesterol (-24%); LDL cholesterol (-19%); and triglycerides (-23%). There were no changes in HDL cholesterol levels, and body mass remained relatively stable.



In the second trial, subjects with elevated cholesterol again benefited from only four weeks of treatment with Sytrinol (300 mg/day). As Table 2 illustrates, treatment with Sytrinol caused significant reductions in: plasma total cholesterol (19.7%); LDL cholesterol (22.01%); apo B (20.9%); and triglycerides (28.4%). Additionally, subjects in the second trial benefited from a significant 5% increase in apo-A1, an important structural protein of HDL
Sytrinol is currently being tested in a long-term, double-blind, crossover randomized study involving 120 men and women with moderately elevated cholesterol levels (total cholesterol >230 mg/dL, LDL > 155 mg/dL). Subjects will receive either 300 mg/day of Sytrinol or a placebo for 12 weeks, followed by a washout period (4 weeks), followed by another 12 weeks where the groups receiving the active compound or placebo will be crossed over.
Only the first 12 weeks (Phase 1) of the long-term study have been completed, yet already the results are proving to be compelling. Compared to placebo, total cholesterol was reduced 30%, LDL cholesterol was reduced 27% and total triglycerides dropped 33%. Additionally, HDL cholesterol levels increased by 4%, resulting in a significant reduction in the LDL/HDL ratio of 30%.

Conclusion

Cholesterol management is a well-established means of maintaining health and preventing premature death from cardiovascular disease. Many people can maintain desirable cholesterol profiles by natural means, including lifestyle modification, exercise, dietary strategies and natural hormone replacement protocols. For those in need of additional cholesterol-lowering options, Sytrinol is a new and important option that can aid in achieving substantial reductions in total cholesterol, LDL cholesterol and triglyceride levels, while improving LDL/HDL ratios. Its lack of the side effects associated with statin drugs makes Sytrinol™ an especially attractive therapy for maintaining healthy cholesterol levels.




A product called CholesLo contains other important ingredients in addition to SYTRINOL itself and it has a pretty good track record without the side effects of Statins and the danger of over dosing on niacin Vit B3 products.











Here are the ingredients of CholesLo AND a link where you can purchase this product::

http://www.choleslo.com/order/riskfree_guarantee.php



This page covers the ingredients found in CholesLo™ and discusses WHY they work, including links to clinical and scientific studies.. Under the below "Supplement Facts", you will see a list of all the specific ingredients and a short overview about their benefits, pros and cons.





Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 80

IngredientsAmount Per Serving%DV/RTI*

Synergy Optimizer™ Technologies - Patent Pending Blend1532 MGS

Lipid Optimizing System [Cholesterol, HDL/LDL & Triglycerides]:
Sytrinol®
Co-Q10 (Ubidecarenone)
Red Yeast Rice (2.5% Extract)
Policosanal (from Sugar Cane - Saccharum species)
Garlic Deoderized (Extract 5% alliin)
Pantesin® d-Pantethine
Guggulsterones (10% Pure Extract; E and Z)
Artichoke Leaf Extract (15% Chlorogenic Acid, 5% Cynarin)
Phytosterols Complex (40% extract from non-GMO pine tree extract)
Liver Cleansing Formula:
Milk Thistle (80% Extract)
NAC (N-Acetyl L-Cysteine)
Insulin/Blood-Sugar Regulator:
R+ Alpha Lipoic Acid (r+ ALA)
Inflammation Reducer:
Turmeric (95% curcuminoids Extract)
Homocysteine Reducing Formula:
Folate (as Folic Acid)
200 mcgs50%
Vitamin B6 (as pyridoxine HCL)
20 mgs1000%
Vitamin B12 (as methylcobalamin)
100 mcgs1667%
Tocotrienols (90% Delta &10% Gamma Tocotrienols)
30 mgs

† Daily Value not established
* Percent Daily Values are based on a 2,000 calorie diet.

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