I am right now on the higher dose:
I am currently taking:
8000 to 9000 mg Vitamin C daily
5000 to 6000 mg of L-lysine daily
1000 mg of L-Proline daily
100 mg Vitamin E daily
50 mg of CoQ10 daily
(Recommended by Dr. Pauling) minimum on high dose:)
6000 mg or (6 games of Vitamin C daily) minimum
4 to 6000 mg of L-Lysine minimum
500 mg to 1000 mg of Proline minimum
The maintenance dose:
3000 mg Vitamin C
1 to 2000 mg of L-Lysine
500 mg L-Proline
As mentioned Dr. Pauling was known to take 18,000 mg of Vitamin C daily for many years. SEE my recent post on vitamin, mineral, herbal supplement SAFETY and historical track record for more information. THEN compare that to the historical track record of 100,000 deaths annually in the USA alone from people taking prescribed prescription drugs exactly as the script was written. (YOU DECIDE).
In any event here is the LINK:
Early Work (Circa 1954)
A good reference book is entitled THE VITAMIN C CONNECTION by Emanuel Cheraskin, M.D., et. al., first published in 1983. Regarding the connection of vitamin C and the development of atherosclerotic plaque, page 98 discusses the early work of Willis (circa 1954-1957):
"Sometimes the turbulence of swiftly moving blood or some other mechanical trauma can cause a permeability or porousness of arterial walls -- allowing infiltration of cholesterol and consequent plaque formation. The integrity or soundness of arterial walls thus acts as a deterrent to develop- ment of atherosclerosis. This soundness depends largely on vitamin C because that nutrient is responsible for the formation and maintenance of their arterial framework and ground substance. The framework consists primarily of the interlacing fibrous protein called collagen, and the ground substance is a biologic cementing medium that binds the collagen into a sturdy unit." The structural picture is completed by an intercellular "glue" that holds connective tissue, muscle, and innerlining cells together.
To demonstrate how restricting C can contribute to ground substance injury, G. C. Willis first worked with guinea pigs. Then, collaborating with Dr. Fishman, he autopsied human aortas for ascorbic-acid contents. Arterial depletion was greatest in areas of the artery subject to extra mechanical stress (such as where they branch or divide). It could also be related to the duration and extent of the victim's illness. Willis and Fishman made note of the fact that a "gross and often complete deficiency of ascorbic acid frequently exists in the arteries of apparently well- nourished hospital autopsy subjects. Old age seems to accentuate the deficiency."
"Willis decided to find out whether vitamin C would reverse atherosclerosis in human beings using serial arteriography. This entails injecting a chemical that makes the arteries visible and them taking a series of x-rays. Subjects were divided into two groups: atherosclerotic patients given 500 mg of ascorbic acid three times each day and controls who weren't. In the C-treated group, 60 % of the subjects showed a reduction of plaque size. In the untreated group, there was no reduction in plaque size; in fact, in 50 percent of the controls, plaque size increased."
Lipoprotein(a) -- VERY BAD LDL
More than five years ago, Nobel prize winning scientist Linus C. Pauling, along with his then associate Dr. Matthias Rath, MD, contributed to the discovery that ordinary LDL (bad) cholesterol is not really the cause of heart disease (occlusive cardiovascular disease) in human beings, any more than calcium or other components that accumulate in atherosclerotic plaques.
Dr. Rath was instrumental in determining that the real culprit in human heart disease was a peculiar variant of LDL called lipoprotein(a). Lipoprotein(a) is an LDL particle with an additional adhesive proteinapo(a) wrapped around it that makes it stick to the walls of injured blood vessels. Pauling and Rath discovered that lipoprotein(a) is found mainly in animals that do not produce vitamin C in their bodies, such as human beings.
When Pauling and Rath were able to show laboratory evidence that not only is plaque build-up prevented "in vivo" in the laboratory, but that such deposits could be reversed, they were awarded the first
U. S. Patentfor reversing heart disease without surgery.
Dr. Pauling lectured on this development for years prior to his death. In 1992 one of these lectures was filmed and is now offered on VHS video tape.
The Real Value of Vitamins According to Dr. Rath,
"Vitamins belong to the most powerful agents in the fight against heart disease. This fact has been established by studies on thousands of people over many years. Here are some important results of recent clinical studies:
Vitamin C cuts heart disease rate almost in half (documented in 11,000 Americans over ten years)
Vitamin E cuts heart disease rate by more than one third (documented in 36,000 Americans over six years.)
Beta Carotene (provitamin A) cuts heart disease rate almost in half (documented in 36,000 Americans).
No prescription drug has ever been shown to help prevent heart disease similar to [vitamins A, C and E]. These results and those of countless other studies are so clear that anybody questioning the value of vitamins in the prevention of heart disease can safely be considered uninformed."
Furthermore, according to Dr. Rath, all blood risk factors known today in clinical cardiology can be neutralized by vitamin C and other essential nutrients.