Melatonin MIGHT INTERFERE with these medications!

action with certain prescriptions. ALWAYS check first with your doctor first before taking any new supplement or prescription.

http://www.webmd.com/vitamins-supplements/ingredientmono-940-melatonin.aspx?activeingredientid=940&activeingredientname=melatonin

EXCERPT From the article:

MELATONIN INTERACTIONS 

Major Interaction Do not take this combination

• Sedative medications (CNS depressants) interacts with MELATONIN
  
  Melatonin might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking melatonin along with sedative medications might cause too much sleepiness.
  Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others.

Moderate Interaction Be cautious with this combination

• Birth control pills (Contraceptive drugs) interacts with MELATONIN
  
  The body makes melatonin. Birth control pills seem to increase how much melatonin the body makes. Taking melatonin along with birth control pills might cause too much melatonin to be in the body.
  Some birth control pills include ethinyl estradiol and levonorgestrel (Triphasil), ethinyl estradiol and norethindrone (Ortho-Novum 1/35, Ortho-Novum 7/7/7), and others.
• Caffeine interacts with MELATONIN
  
  Caffeine might decrease melatonin levels in the body. Taking melatonin along with caffeine might decrease the effectiveness of melatonin supplements.
• Fluvoxamine (Luvox) interacts with MELATONIN
  
  Taking fluvoxamine (Luvox) can increase the amount of melatonin that the body absorbs. Taking melatonin along with fluvoxamine (Luvox) might increase the effects and side effects of melatonin.
• Medications for diabetes (Antidiabetes drugs) interacts with MELATONIN
  
  Melatonin might increase blood sugar. Diabetes medications are used to lower blood sugar. By increasing blood sugar, melatonin might decrease the effectiveness of diabetes medications. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.
  Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
• Medications that decrease the immune system (Immunosuppressants) interacts with MELATONIN
  
  Melatonin might increase the immune system. Taking melatonin along with medications that decrease the immune system might decrease the effectiveness of medications that decrease the immune system.
  Some medications that decrease the immune system include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and others.
• Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with MELATONIN
  
  Melatonin might slow blood clotting. Taking melatonin along with medications that also slow clotting might increase the chances of bruising and bleeding.
  Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.
• Nifedipine GITS (Procardia XL) interacts with MELATONIN
  
  Nifedipine GITS (Procardia XL) is used to lower blood pressure. Taking melatonin might decrease the effectiveness of nifedipine GITS for lowering blood pressure.
• Sedative medications (Benzodiazepines) interacts with MELATONIN
  
  Melatonin might cause sleepiness and drowsiness. Drugs that cause sleepiness and drowsiness are called sedatives. Taking melatonin along with sedative medications might cause too much sleepiness.
  Some of these sedative medications include clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan), and others.
• Verapamil (Calan, Covera, Isoptin, Verelan) interacts with MELATONIN
  
  The body breaks down melatonin to get rid of it. Verapamil (Calan, Covera, Isoptin, Verelan) can increase how quickly the body gets rid of melatonin. Taking melatonin along with verapamil (Calan, Covera, Isoptin, Verelan) might decrease the effectiveness of melatonin.

Minor Interaction Be watchful with this combination

• Flumazenil (Romazicon) interacts with MELATONIN
  
  Flumazenil (Romazicon) might decrease the effects of melatonin. It is not yet clear why this interaction occurs yet. Taking flumazenil (Romazicon) along with melatonin might decrease the effectiveness of melatonin supplements

MORE INFORMATION:

http://www.rxlist.com/melatonin-page2/supplements.htm

Are there safety concerns?

Melatonin is safe for most adults when taken by mouth short-term or applied topically. It can cause some side effects including headache, short-term feelings of depression, daytime sleepiness, dizziness, stomach cramps, and irritability. Do not drive or use machinery for four to five hours after taking melatonin.

Melatonin should not be used in most children. Because of its effects on other hormones, it might interfere with development during adolescence.

Do not take melatonin if:

• You are pregnant or breast-feeding.
• You have high blood pressure.
• You have had a seizure.
• You have diabetes.
• You have cancer.
• You have depression.